A downloadable game

DOWNLOAD REMOVED (it's wildly out of date)

Go buy it on Steam!




Dive into a microscopic alien world, radiating with bioluminescent life and unspeakable horrors. Genome Guardian is a deeply-complex shooter that's easy to pick up but hard to master. Research permanent upgrades to survive 8 game modes, each with multiple ascension levels ("depths").




Pair DNA nucleotides Adenine (rapidfire), Cytosine (precision), Guanine (spread), Thymine (explosive) to discover wild hybrid bioweapons!

  • Bomb + Shotgun combines explosives with spread to create Blast Shotgun!
  • Bomb + Bomb doubles down on explosive power to make Bazooka!
  • Blast Shotgun + Shotgun forms the all-powerful Flak Cannon!




  • 49 Turrets with unique playstyles and functions
  • 96 Perks to mix and match that change how you play
  • 72 Turret & Weapon Mods that can turn shots into sticky mines or bouncing fireballs
  • 32 Mutations that alter the challenges you face each run



  • 20-minute Runs that can be continued in Endless Mode
  • 60 Bassy Electronic Tunes that adapt to the current mood and intensity
  • Accessibility Settings for colourblindness and motion sickness


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